解剖学和形态学
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听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
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药理学和药剂学
生理学
基本医疗保健
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公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::While smokers are known to find smoking-related stimuli motivationally salient, the extent to which former smokers do so is largely unknown. In this study, we collected event-related potential (ERP) data from former and never smokers and compared them to a sample of current smokers interested in quitting who completed...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0038467
更新日期:2015-02-01 00:00:00
abstract::Although the important roles of postquit affect and withdrawal symptoms in the process of smoking cessation have been well established, little is known about the relations between prequit affective trajectories and cessation outcome on the target quit date (TQD). This study examined whether a 16-week course of fluoxet...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0037156
更新日期:2014-10-01 00:00:00
abstract::In the United States, marijuana is the most commonly used illicit drug. Its prevalence is growing, particularly among young adults. Behavioral economic indices of the relative reinforcing efficacy (RRE) of substances have been used to examine the appeal of licit (e.g., alcohol) and illicit (e.g., heroin) drugs. The pr...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0035318
更新日期:2014-06-01 00:00:00
abstract::Existing literature supports the five-factor model (FFM) of personality (i.e., Extraversion, Agreeableness, Conscientiousness, Emotional Stability, and Intellect or Openness) as a comprehensive representation of stable aspects of mood, affect, and behavior. This study evaluated the FFM as a framework for both self-per...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0036607
更新日期:2014-06-01 00:00:00
abstract::Craving has been added as an alcohol use disorder (AUD) symptom in DSM-5 but relatively few nosological studies have directly examined the empirical basis for doing so. The current study investigated the validity of craving as an AUD symptom in a sample of heavy drinking treatment-seeking individuals. Using a semistru...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0034535
更新日期:2014-02-01 00:00:00
abstract::The social environment plays a critical role in determining the likelihood that an individual will use drugs or will develop a drug use disorder. Recent evidence obtained from preclinical studies reveals that proximal social factors (i.e., those factors that are immediately present at the time of drug exposure) exert ...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章,评审
doi:10.1037/a0034669
更新日期:2014-02-01 00:00:00
abstract::Despite depressive symptoms being very common among patients seeking treatment for cocaine dependence, few studies have examined the effects of depressive symptoms on cocaine outpatient treatment outcomes, and there is even less research in the context of Contingency Management (CM). The purpose of this study was to a...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1037/a0033995
更新日期:2013-12-01 00:00:00
abstract::Previous field research has shown that individuals consumed more alcohol and at a faster rate in environments paired with loud music. Theoretically, this effect has been linked to approach/avoidance accounts of how music influences arousal and mood, but no work has tested this experimentally. In the present study, fem...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0034020
更新日期:2013-10-01 00:00:00
abstract::Aerobic exercise can acutely reduce cigarette cravings during periods of nicotine deprivation. The primary aim of this study was to assess the differential effects of light and vigorous intensity aerobic exercise on cigarette cravings, subjective and physiological reactivity to smoking cues, and affect after overnight...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1037/a0032768
更新日期:2013-06-01 00:00:00
abstract::Antipsychotic polypharmacy refers to the clinical practice of treating a patient with two or more antipsychotic drugs concurrently. There is abundant evidence in the clinical literature that treatment with antipsychotic polypharmacy is associated with an increased prevalence of drug side effects compared with monother...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0031228
更新日期:2013-04-01 00:00:00
abstract::Impulsive behavior in heroin-dependent individuals and matched smokers was studied within the framework of temporal discounting. Two well-known effects were examined: the sign and magnitude effects (Kirby, 1997). The study also investigated the relationship between cognitive impulsivity and inhibitory control as measu...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0029657
更新日期:2012-10-01 00:00:00
abstract::Several studies examining both control and substance-dependent populations have found delay discounting to remain stable over time. In this report, we examine whether delay discounting changes in opioid-dependent individuals who complete a 12-week treatment. The 159 subjects who completed discounting assessments at ba...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0027391
更新日期:2012-08-01 00:00:00
abstract::Pramipexole (PPX) is a dopamine agonist medication that has been implicated in the development of pathological gambling and other impulse control disorders. Johnson, Madden, Brewer, Pinkston, and Fowler (2011) reported that PPX increased male rats' preference for gambling-like rewards (those arranged according to a va...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0027117
更新日期:2012-06-01 00:00:00
abstract::Previous research has shown that social drinkers continue to show attentional bias toward alcohol-related stimuli even after consuming a moderate dose of alcohol. In contrast, little is known about how alcohol acutely affects attentional bias in groups at risk to develop alcohol-related problems, such as adults with a...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0026379
更新日期:2012-04-01 00:00:00
abstract::The consumption of alcohol mixed with energy drinks (AmED) has become a popular and controversial practice among young people. Increased rates of impaired driving and injuries have been associated with AmED consumption. The purpose of this study was to examine if the consumption of AmED alters cognitive processing and...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1037/a0026136
更新日期:2012-04-01 00:00:00
abstract::Social learning theory considers self-efficacy as a causal factor in behavior change. However, in line with behavioral theory, recent clinical research suggests self-efficacy ratings may reflect, rather than cause, behavior change. To test these two disparate views, self-efficacy was related to actual smoking abstinen...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0025482
更新日期:2012-02-01 00:00:00
abstract::The link between social influence and drug abuse has long been established in humans. However, preclinical animal models of drug abuse have only recently begun to consider the role of social influence. Since social factors influence the initiation and maintenance of drug use in humans, it is important to include these...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0024682
更新日期:2011-12-01 00:00:00
abstract::Children's alcohol expectancies shift in late childhood/early adolescence in ways thought to lead to increased risk for adolescent alcohol use. The precise nature of this shift and the maturational processes that may influence it remain to be clarified. To these ends, we compared expectancy endorsement by grade across...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0025373
更新日期:2011-12-01 00:00:00
abstract::Relative to intravenous drug self-administration, locomotor activity is easier to measure with high throughput, particularly in mice. Therefore its potential to predict differences in self-administration between genotypes (e.g., targeted mutations, recombinant inbred strains) is appealing, but such predictive value is...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0024798
更新日期:2011-10-01 00:00:00
abstract::Discounting is a behavioral phenomenon in which the value of an outcome diminishes as a function of its increased delay or decreased probability and is related to substance abuse research because of its theoretical ties with behavioral models of impulsive choice. Research to date suggests that hypothetical outcomes us...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0024141
更新日期:2011-08-01 00:00:00
abstract::Difficulty monitoring and inhibiting impulsive behaviors has been reported in marijuana (MJ) smokers; neuroimaging studies, which examined frontal systems in chronic MJ smokers, have reported alterations during inhibitory tasks. Diffusion tensor imaging (DTI) provides a quantitative estimate of white matter integrity ...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0023034
更新日期:2011-06-01 00:00:00
abstract::This report describes a novel procedure for computer-controlled drug-dose determination for IV drug self-administration studies. By modifying the duration of each infusion of a single concentration of a drug solution, five or more unit doses (mg/kg/inj) can be dispensed from the same syringe. The advantages of this pr...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0023037
更新日期:2011-04-01 00:00:00
abstract::Cigarette smoking is highly prevalent among patients who are being treated for opioid-dependence, yet there have been limited scientific efforts to promote smoking cessation in this population. Contingency management (CM) is a behavioral treatment that provides monetary incentives contingent upon biochemical evidence ...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0022039
更新日期:2011-02-01 00:00:00
abstract::Nicotine addiction continues to be the main cause of preventable death in developed countries. Women and teen girls appear to be more vulnerable on certain aspects of nicotine addiction compared with men and boys. While the mechanism of gender differences in nicotine addiction is not yet clear, evidence suggests that ...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章,评审
doi:10.1037/a0021265
更新日期:2010-12-01 00:00:00
abstract::There has been a dramatic rise in the consumption of glucose energy drinks (e.g., Amp, Monster, and Red Bull) in the past decade, particularly among high school and college students. However, little laboratory research has examined the acute objective and subjective effects of energy drinks. The purpose of this study ...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1037/a0021740
更新日期:2010-12-01 00:00:00
abstract::The high comorbidity of posttraumatic stress disorder (PTSD) and alcohol dependence (AD) has been firmly established. Although laboratory studies have examined self-reported craving in response to trauma and alcohol cues, no studies have reported on alcohol-related physiological responding in response to trauma cues i...
journal_title:Experimental and clinical psychopharmacology
pub_type: 临床试验,杂志文章
doi:10.1037/a0019790
更新日期:2010-08-01 00:00:00
abstract::Methylphenidate (MPH) is one of the most widely prescribed drugs for treating attention-deficit hyperactivity disorder. Previous research suggested that MPH is a reinforcer for rats, but not all of the manipulations to show that lever pressing is controlled by the contingency to obtain MPH have been examined. In Exper...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0019814
更新日期:2010-06-01 00:00:00
abstract::Research examining the role of pharmacological therapy in the treatment of children and adolescents with clinical disorders is growing. Clinical disorders that present with comorbid aggression can add a challenge to treatment. Child and adolescent neuropsychiatric disorders associated with aggression include attention...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章,评审
doi:10.1037/a0018059
更新日期:2010-04-01 00:00:00
abstract::Benzodiazepines and alcohol are widely used psychoactive substances that have performance-impairing effects. Research suggests that the impairment profiles for benzodiazepines and alcohol differ, although few cognitive psychopharmacological studies have directly compared these drugs. This double-blind, double-dummy, p...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0018407
更新日期:2010-02-01 00:00:00
abstract::Habitual substance use is associated with attentional bias for stimuli related to the use. The current study tested whether individuals' substance use can be predicted from their attentional bias for concern-related and substance-related stimuli. Participants (N = 71; 54% male) were selected among university students ...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0017294
更新日期:2009-12-01 00:00:00
abstract::The authors investigated the effects of a laboratory stressor task on rapid initial orienting and delayed disengagement aspects of attentional bias for alcohol-related cues in social drinkers (N = 58). Participants were randomly allocated to receive a stress induction or control manipulation before completing a visual...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0017090
更新日期:2009-10-01 00:00:00
abstract::Drug cue reactivity is theoretically and clinically important. The modified Stroop task has been widely used to assess attention capture by drug cues (attentional bias). Attentional bias to drug cues is assumed to reflect the incentive value of those cues, but this has not been directly tested. The authors examined wh...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0016658
更新日期:2009-08-01 00:00:00
abstract::The purpose of this study was to examine the acute effects of alcohol on aggressive behavior in men and women in a laboratory setting. Participants were 526 (261 men and 265 women) healthy social drinkers between 21 and 35 years of age. They were randomly assigned to either an alcohol or a placebo group. Aggression wa...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章,随机对照试验
doi:10.1037/a0016385
更新日期:2009-06-01 00:00:00
abstract::The present study investigated the effects of chronic pre-exposure to methamphetamine on sexual motivation and performance in male Japanese quail. Quail were pre-exposed to methamphetamine (1.0 or 3.0 mg/kg ip) or saline (ip) once daily for 10 days and locomotor activity was measured. After a 10 day washout period, se...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0014505
更新日期:2009-02-01 00:00:00
abstract::A series of experiments in rats explored the possibility that D3/D2 dopamine receptors are involved in behaviors that might be related to compulsion. A series of D3/D2 agonists and antagonists were shown to elicit yawning (D3-receptor mediated) and its inhibition (D2-receptor mediated). In rats with histories of cocai...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/a0014190
更新日期:2008-12-01 00:00:00
abstract::Dependence on and abuse of prescription opioid drugs is now a major health problem, with initiation of prescription opioid abuse exceeding cocaine in young people. Coincident with the emergence of abuse and dependence on prescription opioids, there has been an increased emphasis on the treatment of pain. Pain is now t...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章,评审
doi:10.1037/a0013637
更新日期:2008-10-01 00:00:00
abstract::Smokers are highly reactive to smoking-related cues that are directly linked, or most proximal, to actual smoking behavior (e.g., lit cigarettes). However, over the course of smoking, proximal cues may not be the only stimuli to become strongly associated with smoking. Distal cues, such as the environments in which sm...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/1064-1297.16.3.207
更新日期:2008-06-01 00:00:00
abstract::Drug abuse and impulsive choice are related in humans. In female rats, impulsive choice predicted the rate of acquisition of IV cocaine self-administration. The objectives of the present experiments were to: (a) compare impulsive choice in males and females, (b) extend previous research on impulsive choice and acquisi...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/1064-1297.16.2.165
更新日期:2008-04-01 00:00:00
abstract::The authors tested the hypothesis that the effects of nicotine on affect are moderated by the presence or absence of emotionally positive and negative stimuli and by attentional choice to avoid attending to emotionally negative stimuli. Thirty-two habitual smokers were assigned to tasks allowing attentional freedom to...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/1064-1297.16.1.33
更新日期:2008-02-01 00:00:00
abstract::A retrospective study was conducted to examine aripiprazole's effectiveness and safety in a naturalistic treatment setting in both inpatients and outpatients affected by schizophrenia and other psychotic disorders. All patients with schizophrenia, schizoaffective and delusional disorders, and schizoid and schizotypal ...
journal_title:Experimental and clinical psychopharmacology
pub_type: 杂志文章
doi:10.1037/1064-1297.15.6.569
更新日期:2007-12-01 00:00:00